ATMP operator workshop 24 March 2025
Location: UMCU Auditorium (Q.01.225)
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This workshop is organized for and by ATMP operators, technicians and other experts handling, developing and/or producing ATMPs. The goal of the workshop is to exchange experiences, common practices and challenges, stimulate interaction and foster collaborations.
The workshop is open for other DARE-NL members (and partners who signed a CDA with DARE-NL) with particular interest to attend, but the main goal is for this to be a platform for all operators to share their experiences and learn from each other.
Click here to register.
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Program:
09.00 – 09.30 Welcome with coffee & tea
Session 1: Disinfection (of things brought into the cleanroom)
09.30 – 10.15 STAXS: Training on bringing materials into the cleanroom
10.15 – 10.30 Anouk Donners (UMCU): Training on environmental monitoring
10.30 – 11.30 Break-out session, topics:
- procedures for difficult materials
- environmental monitoring
- cross-contamination and line clearance
- gowning
11.30 – 12.00 Short presentation on main take aways by each group (5-10 minutes)
12.00 – 12.30 Lunch
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Session 2: Cell culture methods
12.30 – 12.45 Cor Berrevoets (EMC): Current manual culture and harvesting procedure
12.45 – 13.30 Maaike van Zon & Saskia Scheij (NKI): Transition to upscaling and automated process on Xuri Cell Expansion System
Discussion with Tessa Mol & Gaby Rijsdijk (Sanquin)
13.30 – 14.00 UMCU/UMCG/LUMC (speakers tbc): Productions on the CliniMACS Prodigy
14.00 – 14.30 Tessa Mol, Gaby Rijsdijk (Sanquin) & Niek van der Zee (AUMC): Productions on the Cocoon Platform
14.30 – 15.00 Break
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Session 3: QC analysis
15.00 – 16.00 Break-out session, topics:
- cell count (incl Round robin) and viability
- characterization assays (e.g. phenotype, flow cytometry)
- functional assays (incl potency)
- microbiology & virus assays (contaminants, virus determinants)
16.00 – 16.45 Short presentation on main take aways by each group
16.45 – 17.00 Concluding remarks
17.00 – 17.30 Drinks
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Directions:
- In the virtual planner choose destination Auditorium (UMC Utrecht):
- Enter the UMC Utrecht via the main entrance;
- Turn right towards Radiology (Reception 19; see blue line on the map);
- When you pass the elevators, turn left and at the end of the corridor turn right into the Q building (route Q);
- Pass through the swinging doors and follow signs for Auditorium Q01