ATMP operator workshop 24 March 2025

Location: UMCU Auditorium (Q.01.225)

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This workshop is organized for and by ATMP operators, technicians and other experts handling, developing and/or producing ATMPs​. The goal of the workshop is to exchange experiences, common practices and challenges, stimulate interaction and foster collaborations​.

The workshop is open for other DARE-NL members (and partners who signed a CDA with DARE-NL) with particular interest to attend, but the main goal is for this to be a platform for all operators to share their experiences and learn from each other.

Click here to register.

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Program:

09.00 – 09.30      Welcome with coffee & tea

Session 1: Disinfection (of things brought into the cleanroom)

09.30 – 10.15    STAXS: Training on bringing materials into the cleanroom

10.15 – 10.30     Anouk Donners (UMCU): Training on environmental monitoring

10.30 – 11.30     Break-out session, topics:

  • procedures for difficult materials
  • environmental monitoring
  • cross-contamination and line clearance
  • gowning

11.30 – 12.00     Short presentation on main take aways by each group (5-10 minutes)

12.00 – 12.30     Lunch

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Session 2: Cell culture methods

12.30 – 12.45     Cor Berrevoets (EMC): Current manual culture and harvesting procedure

12.45 – 13.30     Maaike van Zon & Saskia Scheij (NKI): Transition to upscaling and automated process​ on Xuri Cell Expansion System

Discussion with Tessa Mol & Gaby Rijsdijk (Sanquin)

13.30 – 14.00     UMCU/UMCG/LUMC (speakers tbc): Productions ​on the CliniMACS Prodigy

14.00 – 14.30     Tessa Mol, Gaby Rijsdijk (Sanquin) & Niek van der Zee (AUMC): Productions on the Cocoon Platform ​

14.30 – 15.00     Break​

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Session 3: QC analysis

15.00 – 16.00     Break-out session, topics:

  • cell count (incl Round robin) and viability
  • characterization assays (e.g. phenotype, flow cytometry)
  • functional assays (incl potency)
  • microbiology & virus assays (contaminants, virus determinants)

16.00 – 16.45     Short presentation on main take aways by each group

16.45 – 17.00     Concluding remarks

17.00 – 17.30     Drinks​

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Directions:

  • In the virtual planner choose destination Auditorium (UMC Utrecht):
  • Enter the UMC Utrecht via the main entrance;
  • Turn right towards Radiology (Reception 19; see blue line on the map);
  • When you pass the elevators, turn left and at the end of the corridor turn right into the Q building (route Q);
  • Pass through the swinging doors and follow signs for Auditorium Q01